SCHEMBL1127096

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29509033	0.89	ADRA2C (0.62)	ADRA2CHTR3ADRD2DRD3NCF1
	SCHEMBL3623865	0.89	ADRA2C (0.62)	ADRA2CHTR3ADRD2DRD3NCF1
	SCHEMBL3616397	0.83	ADRA2C (0.56)	ADRA2CHTR3ADRD2DRD3NCF1
	SCHEMBL1509507	0.81	ADRA2C (0.72)	ADRA2CHTR3ADRD2DRD3NCF1
	SCHEMBL31172405	0.81	ADRA2C (0.72)	ADRA2CHTR3ADRD2DRD3NCF1
	SCHEMBL1926749	0.81	ADRA2C (1.00)	ADRA2CHTR3ADRD2DRD3NCF1
	SCHEMBL29586390	0.81	ADRA2C (1.00)	ADRA2CHTR3ADRD2DRD3NCF1
	SCHEMBL6002186	0.79	DRD2 (0.69)	ADRA2CHTR3ADRD2DRD3NCF1
	SCHEMBL6002177	0.78	HTR1A (0.62)	ADRA2CHTR3ADRD2DRD3NCF1
	SCHEMBL28311804	0.78	ADRA2C (0.53)	ADRA2CHTR3ADRD2DRD3NCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.