Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | MAP2 | P11137 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127700 | 0.77 | KDM4E (0.40) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL1126976 | 0.70 | JAK3 (0.33) | — | |
| SCHEMBL16500354 | 0.69 | PRKAB2 (0.41) | PYGLNOTUMBCL2CYP1A2 | |
| SCHEMBL1126618 | 0.69 | EGFR (0.40) | TP53CYP1A2 | |
| SCHEMBL1127376 | 0.65 | LMNA (0.40) | TP53NPC1RAB9ALMNAMAPT | |
| SCHEMBL11257788 | 0.64 | HEXA (0.41) | TP53NPC1RAB9ALMNAMAPT | |
| SCHEMBL1126973 | 0.62 | FFAR1 (0.40) | ALDH1A1MAP2HSD17B10CYP1A2 | |
| SCHEMBL15497049 | 0.61 | TP53 (0.52) | TP53NPC1RAB9ALMNAMAPT | |
| SCHEMBL9269074 | 0.61 | MAOB (0.53) | ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1127778 | 0.61 | LMNA (0.39) | TP53RAB9ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |