Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127376 | 0.93 | LMNA (0.40) | LMNATDP1ALDH1A1RAB9AGAA | |
| SCHEMBL1126902 | 0.85 | LMNA (0.38) | LMNATDP1ALDH1A1RAB9AKDM4E | |
| SCHEMBL1126894 | 0.83 | LMNA (0.48) | LMNAALDH1A1RAB9AGAAHTT | |
| SCHEMBL1126936 | 0.83 | CSF1R (0.39) | LMNATDP1ALDH1A1RAB9AKDM4E | |
| SCHEMBL1126974 | 0.83 | LMNA (0.43) | LMNATDP1ALDH1A1RAB9AGAA | |
| SCHEMBL1127399 | 0.81 | LMNA (0.35) | LMNATDP1ALDH1A1RAB9AKDM4E | |
| SCHEMBL1127366 | 0.79 | LMNA (0.37) | LMNATDP1ALDH1A1RAB9AKDM4E | |
| SCHEMBL1127186 | 0.79 | MTNR1A (0.45) | LMNATDP1ALDH1A1RAB9AKDM4E | |
| SCHEMBL1127408 | 0.79 | RAB9A (0.39) | LMNATDP1ALDH1A1RAB9AKDM4E | |
| SCHEMBL1127422 | 0.78 | RAB9A (0.41) | LMNAALDH1A1RAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |