Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | FRK | P42685 | 1/20 | 0.34 |
| ▸ | BLK | P51451 | 1/20 | 0.34 |
| ▸ | NEK4 | P51957 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.34 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.34 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126974 | 0.67 | LMNA (0.43) | MCL1ALDH1A1CYP1A2CYP2C19CLK4 | |
| SCHEMBL1127376 | 0.67 | LMNA (0.40) | MCL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15161899 | 0.64 | ALDH1A1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL1156618 | 0.63 | LMNA (0.47) | KDM5AKDM4CKDM5BKDM4EALDH1A1 | |
| SCHEMBL8816288 | 0.63 | TAAR1 (0.56) | KDM4EALDH1A1ALOX5TSHR | |
| SCHEMBL1127778 | 0.63 | LMNA (0.39) | MCL1KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL1127700 | 0.62 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10CASP7 | |
| SCHEMBL1127138 | 0.62 | PYGL (0.34) | ALDH1A1HSD17B10MAP2CYP1A2 | |
| SCHEMBL1126976 | 0.62 | JAK3 (0.33) | — | |
| SCHEMBL9219794 | 0.62 | MAPT (0.36) | KDM4EALDH1A1HSD17B10TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |