Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253114 | 0.81 | AMY1A (0.47) | MAPTSMN1; SMN2TP53HTTRAB9A | |
| SCHEMBL11253305 | 0.78 | NPC1 (0.48) | MAPTSMN1; SMN2TP53HTTRAB9A | |
| SCHEMBL11251140 | 0.71 | ALDH1A1 (0.40) | MAPTSMN1; SMN2TP53HTTRAB9A | |
| SCHEMBL11262388 | 0.70 | AMY1A (0.37) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL11264095 | 0.70 | AMY1A (0.34) | DRD3RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL11250100 | 0.69 | KDM4E (0.42) | MAPTSMN1; SMN2TP53HTTRAB9A | |
| SCHEMBL11247352 | 0.69 | NPC1 (0.48) | MAPTSMN1; SMN2TP53HTTRAB9A | |
| SCHEMBL11255428 | 0.68 | ALDH1A1 (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL31063784 | 0.68 | ACHE (0.74) | DRD3MAPTSMN1; SMN2TP53HTT | |
| SCHEMBL11624627 | 0.68 | ACHE (0.74) | DRD3MAPTSMN1; SMN2TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | disclosed |