SCHEMBL1127160

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4540125	0.77	ALDH1A1 (0.49)	KMT2AMEN1MAPTNPSR1SMN1; SMN2
	SCHEMBL15051320	0.71	ALDH1A1 (0.45)	KMT2AMEN1MAPTSMN1; SMN2NPC1
	SCHEMBL15051322	0.71	ALDH1A1 (0.45)	KMT2AMEN1MAPTSMN1; SMN2NPC1
	SCHEMBL2471403	0.70	PDE7A (0.48)	KMT2AMEN1MAPTSMN1; SMN2MAPK1
	SCHEMBL15051234	0.70	ALDH1A1 (0.44)	KMT2AMEN1MAPTNPSR1SMN1; SMN2
	SCHEMBL3686179	0.68	ALDH1A1 (0.59)	KMT2AMEN1MAPTSMN1; SMN2NPC1
	SCHEMBL1126417	0.67	L3MBTL1 (0.81)	KMT2AMEN1MAPTNPSR1SMN1; SMN2
	SCHEMBL3643249	0.66	ALDH1A1 (0.52)	KMT2AMEN1MAPTSMN1; SMN2MAPK1
	SCHEMBL29271622	0.66	SMN1; SMN2 (0.46)	KMT2AMEN1MAPTSMN1; SMN2MAPK1
	SCHEMBL10913298	0.64	HSD17B10 (0.56)	KMT2AMEN1MAPTSMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.