SCHEMBL1127215

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1993234	0.95	MAPT (0.36)	LMNAUSP2MAPTTSHRSMN1; SMN2
	SCHEMBL1126636	0.93	GRIN2D (0.38)	LMNAUSP2MAPTTSHRSMN1; SMN2
	SCHEMBL1127290	0.92	LMNA (0.37)	LMNAUSP2MAPTTSHRKMT2A
	SCHEMBL1126832	0.90	MAPT (0.37)	LMNAMAPTTSHRSMN1; SMN2KMT2A
	SCHEMBL1127217	0.90	LMNA (0.36)	LMNAUSP2MAPTTSHRKMT2A
	SCHEMBL1126741	0.89	LMNA (0.39)	LMNAUSP2MAPTTSHRKMT2A
	SCHEMBL1126633	0.89	MAPT (0.36)	LMNAUSP2MAPTTSHRSMN1; SMN2
	SCHEMBL1126732	0.89	MAPT (0.38)	LMNAUSP2MAPTTSHRKMT2A
	SCHEMBL1126552	0.88	MAPT (0.39)	LMNAUSP2MAPTTSHRKMT2A
	SCHEMBL1127558	0.88	ALDH1A1 (0.37)	LMNAUSP2MAPTTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.