Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819237 | 0.88 | BCL2A1 (0.49) | BCL2A1ALDH1A1HTR1ARAD51 | |
| SCHEMBL11425493 | 0.87 | MGLL (0.51) | MGLLBCL2A1ALOX5ADRA1AADRA1B | |
| SCHEMBL11272449 | 0.83 | MGLL (0.50) | MGLLBCL2A1ALOX5ADRA1AADRA1B | |
| SCHEMBL11427213 | 0.83 | BCL2A1 (0.44) | MGLLBCL2A1ALOX5ADRA1AADRA1B | |
| SCHEMBL9819424 | 0.81 | BCL2A1 (0.49) | BCL2A1ADRA1BALDH1A1MAPTHTR1A | |
| SCHEMBL9819264 | 0.81 | ADRA1B (0.47) | BCL2A1ADRA1AADRA1BADRA1DALDH1A1 | |
| SCHEMBL9819256 | 0.81 | MEN1 (0.47) | MGLLALDH1A1MAPTPOLBHSD17B10 | |
| SCHEMBL11431742 | 0.80 | OPRK1 (0.47) | MGLLBCL2A1ALOX5ADRA1BMAPT | |
| Hydrochloric Acid SCHEMBL9819442 | 0.79 | ADRA2C (0.44) | ALDH1A1MAPTPOLBL3MBTL1TP53 | |
| SCHEMBL3786268 | 0.79 | MGLL (0.61) | MGLLBCL2A1ALOX5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |