Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 8/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630564 | 0.89 | GRIA4 (0.56) | GRIA4GRIA2TSHRMEN1KMT2A | |
| SCHEMBL24584762 | 0.85 | GRIA4 (0.50) | GRIA4GRIA2MEN1KMT2AUSP2 | |
| SCHEMBL19663897 | 0.84 | GRIA4 (0.61) | GRIA4GRIA2TSHRKMT2AUSP2 | |
| SCHEMBL29859653 | 0.84 | GRIA2 (0.49) | GRIA4GRIA2 | |
| SCHEMBL24584088 | 0.84 | GRIA2 (0.49) | GRIA4GRIA2 | |
| SCHEMBL1127504 | 0.81 | GRIA4 (0.58) | GRIA4GRIA2TSHRPRNPPPARG | |
| SCHEMBL24584785 | 0.80 | GRIA4 (0.57) | GRIA4GRIA2TSHRKMT2ALMNA | |
| SCHEMBL1127427 | 0.80 | KDM4E (0.45) | GRIA4GRIA2TSHRMEN1KMT2A | |
| SCHEMBL26597135 | 0.80 | GRIA2 (0.46) | GRIA4GRIA2TSHRMEN1KMT2A | |
| SCHEMBL1126774 | 0.79 | GRIA4 (0.46) | GRIA4GRIA2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327423-A1 | A SERIES OF PYRROLE DERIVATIVES AND THEIR PREPARATION METHOD AND THERAPEUTIC USE | Shenzhen Sungening Biological Co., Ltd (CN) | 2024-10-03 | — | — | US | disclosed |
| US-11819503-B2 | Method of treating coccidioides infection | F2G LTD (GB) | 2023-11-21 | — | — | US | disclosed |
| US-11819503-B2 | Method of treating coccidioides infection | F2G LTD (GB) | 2023-11-21 | — | — | US | disclosed |
| US-11819503-B2 | Method of treating coccidioides infection | F2G LTD (GB) | 2023-11-21 | — | — | US | disclosed |
| EP-4265621-A1 | PYRROLE DERIVATIVE, AND PREPARATION METHOD AND USE THEREFOR | Shenzhen Sungening Bio-Medical Co., Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |
| EP-4265621-A1 | PYRROLE DERIVATIVE, AND PREPARATION METHOD AND USE THEREFOR | Shenzhen Sungening Bio-Medical Co., Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |
| CN-109982704-B | Pharmaceutical preparation | F2G有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116675704-A | Pyrrole derivative and preparation method and application thereof | 深圳市祥根生物医药有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-114644634-B | Pyrrole derivative and preparation method and application thereof | 深圳市祥根生物医药有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-111096967-B | Antifungal agent | F2G有限公司 | 2023-03-10 | — | — | CN | disclosed |
| US-9452168-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2016-09-27 | — | — | US | disclosed |
| WO-2016079536-A1 | ANTIFUNGAL AGENTS | F2G LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |
| US-20150238500-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-08-27 | — | — | US | disclosed |
| US-8993574-B2 | Pyrrole antifungal agents | F2G LTD (GB) | 2015-03-31 | — | — | US | disclosed |
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| US-20110152285-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2011-06-23 | — | — | US | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327423-A1 | A SERIES OF PYRROLE DERIVATIVES AND THEIR PREPARATION METHOD AND THERAPEUTIC USE | DHODH, PPOX, HPD | GRIA4 2713/4885GRIA2 3153/4885TSHR 4290/4885 |
| US-20110152285-A1 | PYRROLE ANTIFUNGAL AGENTS | FOXM1, PYCR1, ARG1 | GRIA4 2979/4885GRIA2 2791/4885TSHR 1769/4885 |
| US-20150238500-A1 | PYRROLE ANTIFUNGAL AGENTS | FOXM1, PYCR1, ARG1 | GRIA4 2979/4885GRIA2 2791/4885TSHR 1769/4885 |
| US-11819503-B2 | Method of treating coccidioides infection | DPM1, OAT, OTC | GRIA4 3761/4885GRIA2 3820/4885TSHR 4619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.