Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337491 | 0.88 | ALDH1A1 (0.57) | ADORA2AADORA1ALDH1A1LMNANPSR1 | |
| SCHEMBL28303870 | 0.78 | ADORA2A (0.52) | ADORA2AADORA1ALDH1A1LMNANPSR1 | |
| SCHEMBL11268851 | 0.78 | SMN1; SMN2 (0.53) | ADORA2AADORA1ALDH1A1LMNANPSR1 | |
| SCHEMBL11273639 | 0.74 | GPR84 (0.49) | ADORA2AADORA1ALDH1A1LMNANPSR1 | |
| SCHEMBL11280072 | 0.74 | NPSR1 (0.47) | ADORA2AADORA1ALDH1A1LMNANPSR1 | |
| SCHEMBL1006428 | 0.71 | PAX8 (0.63) | ALDH1A1SMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL24124452 | 0.71 | SMN1; SMN2 (0.54) | ALDH1A1LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL22724736 | 0.71 | SMN1; SMN2 (0.54) | ALDH1A1LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL14280962 | 0.71 | ADORA2A (0.54) | ADORA2AALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL11778554 | 0.69 | MAPK1 (0.56) | ADORA2AADORA1ALDH1A1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310551-A | Pharmacologically active substituted 1,2,4-triazines | DIAMOND SHAMROCK CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |
| US-4251527-A | ANTIINFLAMMATORY AGENTS | DIAMOND SHAMROCK CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4157392-A | HYPOTENSIVE AGENTS, ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS AND NERVOUS SYSTEM EFFECTS | DIAMOND SHAMROCK CORPORATION (US) | 1979-06-05 | — | — | US | disclosed |