Isophthalic Acid

Isophthalic Acid

SCHEMBL7913012

O=C(O)c1ccc(OC(=O)c2ccc(C(=O)O)cc2)cc1.O=C(O)c1cccc(C(=O)O)c1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
GAA P10253 1/20 0.59
MAPT P10636 4/20 0.58
TDP1 Q9NUW8 3/20 0.58
PARP10 Q53GL7 1/20 0.58
KMO O15229 1/20 0.56
KMT2A Q03164 5/20 0.54
MEN1 O00255 2/20 0.54
HSD17B10 Q99714 1/20 0.51
ALDH1A1 P00352 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
PKM P14618 1/20 0.51
RAB9A P51151 1/20 0.49
AKR1C3 P42330 1/20 0.49
NR4A2 P43354 1/20 0.48
MRGPRX4 Q96LA9 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11040365 0.92 PARP10 (0.59) LMNAGAAMAPTTDP1PARP10
Isophthalic Acid SCHEMBL2889737 0.90 PARP10 (0.61) MAPTTDP1PARP10KMT2AMEN1
SCHEMBL23202513 0.90 PARP10 (0.66) LMNAGAAMAPTTDP1PARP10
SCHEMBL9696360 0.90 PARP10 (0.66) LMNAGAAMAPTTDP1PARP10
SCHEMBL9189715 0.90 HSD17B10 (0.62) LMNAGAAMAPTTDP1PARP10
Terephthalic Acid SCHEMBL6660728 0.88 AKR1C3 (0.58) MAPTTDP1PARP10KMT2AMEN1
SCHEMBL11273083 0.88 PARP10 (0.58) LMNAGAAMAPTTDP1PARP10
Biphenyl SCHEMBL9780962 0.88 MAPT (0.58) LMNAGAAMAPTTDP1PARP10
SCHEMBL4135573 0.88 LMNA (0.54) LMNAGAAMAPTTDP1PARP10
Paraben SCHEMBL3853193 0.88 LMNA (0.54) LMNAGAAMAPTTDP1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6229675-B1 Swing arm actuator for magnetic disk unit NIPPON PETROCHEMICALS CO., LTD (JP) 2001-05-08 US disclosed
EP-0637039-A1 ACTUATOR FOR DISK UNIT NIPPON PETROCHEMICALS CO., LTD. (JP) 1995-02-01 EP disclosed