Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 7/20 | 0.47 |
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | HTR2A | P28223 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 5/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274363 | 0.88 | DRD2 (0.59) | SLC6A4SLC6A2DRD2HTR1AHTR2A | |
| SCHEMBL11271731 | 0.87 | SLC6A4 (0.52) | SLC6A4SLC6A2DRD2HTR1AHTR2A | |
| SCHEMBL11299358 | 0.86 | HTR7 (0.59) | DRD2DRD3DRD1SIGMAR1HTR7 | |
| SCHEMBL11270104 | 0.85 | HTR1A (0.56) | DRD2HTR1AHTR2ADRD3HRH3 | |
| SCHEMBL11307110 | 0.85 | SLC6A4 (0.57) | SLC6A4SLC6A2DRD2HTR1AHTR2A | |
| SCHEMBL11268707 | 0.83 | SLC6A4 (0.65) | SLC6A4SLC6A2DRD2DRD3HRH3 | |
| SCHEMBL11279021 | 0.81 | S1PR5 (0.55) | SLC6A4SLC6A2DRD2HTR1AHTR2A | |
| SCHEMBL11275227 | 0.81 | KCNH2 (0.60) | SLC6A4SLC6A2DRD2DRD3SIGMAR1 | |
| SCHEMBL11278314 | 0.80 | SLC6A4 (0.70) | SLC6A4SLC6A2DRD2DRD3HRH3 | |
| SCHEMBL11290067 | 0.79 | HTR1A (0.59) | SLC6A4SLC6A2DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |
| EP-0021368-A1 | Piperazinylalkoxyindanes and acid addition salts thereof | MITSUBISHI KASEI CORPORATION (JP) | 1981-01-07 | — | — | EP | disclosed |