Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306526 | 0.87 | HTR1A (0.48) | HTR7DRD2SIGMAR1ABCB1DRD3 | |
| SCHEMBL11300075 | 0.87 | KCNH2 (0.62) | HTR7DRD2SIGMAR1ABCB1ADRA1A | |
| SCHEMBL11284128 | 0.86 | HTR7 (0.59) | HTR7DRD2SIGMAR1ABCB1DRD3 | |
| SCHEMBL11273088 | 0.86 | SLC6A4 (0.52) | HTR7DRD2SIGMAR1DRD3ADRA1A | |
| SCHEMBL11276751 | 0.85 | HTR7 (0.58) | HTR7DRD2SIGMAR1ABCB1DRD3 | |
| SCHEMBL11280944 | 0.85 | HTR7 (0.60) | HTR7DRD2SIGMAR1ABCB1DRD3 | |
| SCHEMBL11285131 | 0.84 | DRD2 (0.69) | HTR7DRD2SIGMAR1 | |
| SCHEMBL11275227 | 0.83 | KCNH2 (0.60) | HTR7DRD2SIGMAR1ABCB1DRD3 | |
| SCHEMBL11270104 | 0.82 | HTR1A (0.56) | HTR7DRD2SIGMAR1DRD3ADRA1A | |
| SCHEMBL11276314 | 0.82 | HTR7 (0.59) | HTR7DRD2SIGMAR1ABCB1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |
| EP-0021368-A1 | Piperazinylalkoxyindanes and acid addition salts thereof | MITSUBISHI KASEI CORPORATION (JP) | 1981-01-07 | — | — | EP | disclosed |