Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269114 | 0.86 | PLA2G10 (0.44) | PLA2G10L3MBTL1HPGDLMNATOP2A | |
| SCHEMBL11270567 | 0.80 | P2RX3 (0.42) | — | |
| SCHEMBL11274778 | 0.76 | TOP2A (0.32) | L3MBTL1HPGDLMNATOP2ATOP2B | |
| SCHEMBL11281016 | 0.76 | LMNA (0.33) | L3MBTL1HPGDLMNATSHR | |
| SCHEMBL11266028 | 0.72 | PLA2G10 (0.35) | PLA2G10L3MBTL1HPGDLMNATOP2A | |
| SCHEMBL11298309 | 0.72 | TDP1 (0.53) | L3MBTL1LMNATDP1 | |
| SCHEMBL11279540 | 0.71 | P2RX3 (0.43) | — | |
| SCHEMBL11267837 | 0.71 | SCN9A (0.37) | HPGDLMNAALOX15TSHRMAPT | |
| SCHEMBL11273154 | 0.71 | L3MBTL1 (0.38) | PLA2G10L3MBTL1HPGDLMNATOP2A | |
| SCHEMBL11274667 | 0.70 | P2RX3 (0.34) | HPGDTSHRALDH1A1SMN1; SMN2ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338326-A | PESTICIDES | UNION CARBIDE CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |