Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.36 |
| ▸ | HTR3B | O95264 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755432 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15463133 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL12336906 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3313983 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13871377 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6208251 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1813567 | 0.76 | TXNRD1 (0.47) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6152341 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20683979 | 0.74 | ALDH1A1 (0.36) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20198346 | 0.74 | ALOX12 (0.43) | ALDH1A1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026316-B1 | PROCESS FOR THE PREPARATION OF 4-NITROSO-DIPHENYL AMINE | BAYER AG (DE) | 1982-05-26 | — | — | EP | disclosed |
| US-4324913-A | REARRANGEMENT OF N-NITROSODIPHENYLAMINE, HYDROCHLORIC ACID, O-DICHLOROBENZENE SOLVENT | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| EP-0026316-A1 | Process for the preparation of 4-nitroso-diphenyl amine | BAYER AG (DE) | 1981-04-08 | — | — | EP | disclosed |