Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276382 | 0.72 | BRD4 (0.47) | ALDH1A1 | |
| SCHEMBL11275319 | 0.70 | CHRM1 (0.43) | — | |
| SCHEMBL26976648 | 0.70 | LIG1 (0.42) | RORCALDH1A1LIG1LMNA | |
| SCHEMBL10460507 | 0.68 | QDPR (0.62) | RAB9ADPP4DPP7 | |
| SCHEMBL18711298 | 0.66 | RORC (0.44) | RORCNR1I2ALDH1A1CYP2D6 | |
| SCHEMBL20491450 | 0.65 | RORC (0.44) | RORCNR1I2ALDH1A1CYP2D6 | |
| SCHEMBL31726526 | 0.65 | MEN1 (0.46) | RORC | |
| SCHEMBL17523305 | 0.64 | LIG1 (0.40) | RORCLIG1TP53 | |
| SCHEMBL17523300 | 0.64 | LIG1 (0.40) | RORCLIG1TP53 | |
| SCHEMBL20491252 | 0.63 | HSD11B1 (0.47) | RORCNR1I2ALDH1A1CYP2D6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321379-A | NEUROLEPTIC AGENTS AND ANALGESICS | AMERICAN CYANAMID COMPANY (US) | 1982-03-23 | — | — | US | claimed |