SCHEMBL26976648

SCHEMBL26976648

CC1(C)OC(=O)CC1c1ccc(F)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.42
CYP2C19 P33261 1/20 0.40
RORC P51449 1/20 0.39
KDM1A O60341 1/20 0.39
RCOR1 Q9UKL0 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HSD11B1 P28845 1/20 0.38
RECQL P46063 1/20 0.37
GSK3B P49841 1/20 0.36
BACE1 P56817 1/20 0.36
MAP1LC3B Q9GZQ8 1/20 0.36
ALDH1A1 P00352 3/20 0.36
MAOB P27338 5/20 0.36
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26976788 0.84 ALDH1A1 (0.39) CYP2C19RECQLMAP1LC3BALDH1A1MAOB
SCHEMBL10748346 0.82 KDM1A (0.46) CYP2C19KDM1AALDH1A1MAOBTSHR
SCHEMBL17523300 0.79 LIG1 (0.40) LIG1CYP2C19RORCKDM1ARCOR1
SCHEMBL17523305 0.79 LIG1 (0.40) LIG1CYP2C19RORCKDM1ARCOR1
SCHEMBL10746143 0.73 CYP2C19 (0.49) LIG1CYP2C19RORCKDM1ARCOR1
SCHEMBL11273632 0.70 RORC (0.40) LIG1RORCALDH1A1LMNA
SCHEMBL17525817 0.70 RORC (0.36) LIG1RORCKDM1ARCOR1TDP1
SCHEMBL16056190 0.70 RORC (0.36) LIG1RORCKDM1ARCOR1TDP1
SCHEMBL16066029 0.70 RORC (0.36) LIG1RORCKDM1ARCOR1TDP1
SCHEMBL26976730 0.69 GSK3B (0.43) LIG1CYP2C19RORCKDM1ARCOR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240188565-A1 GLOBODERA PALLIDA CONTROL AGENT NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (JP) 2024-06-13 US disclosed
EP-4298907-A1 GLOBODERA PALLIDA CONTROL AGENT NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (JP) 2024-01-03 EP disclosed
WO-2022181170-A1 GLOBODERA PALLIDA CONTROL AGENT 国立研究開発法人農業・食品産業技術総合研究機構 2022-09-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240188565-A1 GLOBODERA PALLIDA CONTROL AGENT GHRHR, BRIX1, RBX1 LIG1 2500/4885CYP2C19 4397/4885RORC 2468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.