Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275319 | 0.79 | CHRM1 (0.43) | BRD4SMN1; SMN2TSHRKMT2A | |
| SCHEMBL12835956 | 0.78 | DRD2 (0.47) | KMT2A | |
| SCHEMBL11273632 | 0.72 | RORC (0.40) | ALDH1A1 | |
| SCHEMBL17583802 | 0.72 | GAA (0.52) | GAASMN1; SMN2L3MBTL1TSHRKMT2A | |
| SCHEMBL17732414 | 0.72 | GAA (0.52) | GAASMN1; SMN2L3MBTL1TSHRKMT2A | |
| SCHEMBL17589052 | 0.72 | GAA (0.52) | GAASMN1; SMN2L3MBTL1TSHRKMT2A | |
| SCHEMBL7435969 | 0.71 | L3MBTL1 (0.51) | APPGAASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL21581202 | 0.70 | OPRD1 (0.63) | APPMAPTTSHR | |
| SCHEMBL16182201 | 0.70 | OPRD1 (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL11860423 | 0.69 | SIGMAR1 (0.54) | BRD4APPMAPTTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321379-A | NEUROLEPTIC AGENTS AND ANALGESICS | AMERICAN CYANAMID COMPANY (US) | 1982-03-23 | — | — | US | disclosed |