Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | HTR7 | P34969 | 5/20 | 0.43 |
| ▸ | DRD3 | P35462 | 7/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600153 | 0.82 | PARP1 (0.58) | PARP1HTR1AHTR7DRD3DRD2 | |
| Citric Acid SCHEMBL11067205 | 0.77 | PDE10A (0.44) | PARP1HTR1AHTR7DRD3DRD2 | |
| Citric Acid SCHEMBL11067947 | 0.70 | HTR7 (0.48) | HTR1AHTR7DRD3DRD2DRD4 | |
| Centhaquine SCHEMBL29991187 | 0.67 | DRD3 (0.56) | HTR1ADRD3DRD2DRD4HTR2A | |
| Citric Acid SCHEMBL10604868 | 0.67 | HTR7 (0.47) | HTR1AHTR7DRD3DRD2HTR2A | |
| SCHEMBL11065952 | 0.66 | PARP1 (0.53) | PARP1HTR1AHTR7DRD3DRD2 | |
| SCHEMBL712211 | 0.66 | PARP1 (0.53) | PARP1HTR1AHTR7DRD3DRD2 | |
| SCHEMBL11073089 | 0.65 | PDE10A (0.48) | PARP1HTR1AHTR7DRD3DRD2 | |
| SCHEMBL11847564 | 0.65 | PARP1 (0.62) | PARP1HTR1AHTR7DRD2HTR2A | |
| SCHEMBL8689425 | 0.64 | DRD4 (0.76) | PARP1HTR1AHTR7DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360674-A | Naphth[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1982-11-23 | — | — | US | disclosed |