SCHEMBL11273757

SCHEMBL11273757

O=c1n(-c2cc(Cl)cc(Cl)c2)cnn1SC(F)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11267538 0.88 CYP11B2 (0.32) CYP11B2
SCHEMBL11270305 0.87 MAPT (0.39) CYP11B2
SCHEMBL11260766 0.83 PTGS2 (0.36)
SCHEMBL11265484 0.82 ALDH1A1 (0.36)
SCHEMBL11266860 0.81 PPARD (0.35) CYP11B2
SCHEMBL11276227 0.80 ALDH1A1 (0.38)
SCHEMBL11273387 0.79 MEN1 (0.38)
SCHEMBL11266444 0.79 ALDH1A1 (0.41)
SCHEMBL11266715 0.79 HCAR1 (0.43) CYP11B2
SCHEMBL11271704 0.78 HTT (0.51) CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4350701-A 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi BASF AKTIENGESELLSCHAFT (DE) 1982-09-21 US disclosed