Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953669 | 0.73 | MEN1 (0.42) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL14879169 | 0.73 | PRCP (0.51) | KDM4EACEPKMKMT2AALDH1A1 | |
| SCHEMBL7344344 | 0.72 | ACE (0.50) | KDM4EACEKMT2AMEN1ALDH1A1 | |
| SCHEMBL19953491 | 0.72 | F11 (0.50) | KDM4EACENPSR1KMT2AMEN1 | |
| SCHEMBL19953658 | 0.72 | F11 (0.50) | KDM4EACENPSR1KMT2AMEN1 | |
| SCHEMBL11273243 | 0.71 | KMT2A (0.42) | KDM4EPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL20113096 | 0.71 | GRM7 (0.55) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6370100 | 0.70 | CHRM2 (0.53) | KMT2AMEN1 | |
| SCHEMBL28047413 | 0.70 | DPP4 (0.37) | ACETSHRKCNH2CYP1A2CYP2C19 | |
| SCHEMBL4720088 | 0.70 | PIN1 (0.52) | KDM4EKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351842-A | N-Cyclopropylisoindolines | GLAXO LABORATORIES LIMITED (GB) | 1982-09-28 | — | — | US | disclosed |