Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960636 | 0.85 | HDAC4 (0.43) | MEN1KMT2ANOTUMSLC6A4TSHR | |
| SCHEMBL19953586 | 0.82 | ACE (0.35) | NOTUMKDM4EALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL20166097 | 0.82 | GRM7 (0.39) | MEN1KMT2ANOTUMKDM4EOPRM1 | |
| SCHEMBL20113096 | 0.81 | GRM7 (0.55) | MEN1KMT2AKDM4EKCNH2ALDH1A1 | |
| SCHEMBL19953522 | 0.80 | ACE (0.47) | NOTUMHPGD | |
| SCHEMBL19953652 | 0.80 | ACE (0.47) | NOTUMHPGD | |
| SCHEMBL20182932 | 0.79 | SIGMAR1 (0.38) | MEN1KMT2ANOTUMKDM4EKCNH2 | |
| SCHEMBL14790130 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL19960827 | 0.74 | ANPEP (0.40) | MEN1KMT2ANOTUMKDM4EALDH1A1 | |
| SCHEMBL1998760 | 0.74 | HDAC4 (0.44) | MEN1KMT2ANOTUMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |