Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 6/20 | 0.52 |
| ▸ | HTR1A | P08908 | 5/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265017 | 0.97 | DRD2 (0.69) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11275993 | 0.86 | LMNA (0.67) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11267243 | 0.84 | DRD2 (0.62) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11269670 | 0.83 | HTR2A (0.55) | DRD2HTR2AHTR1ASLC6A4FAAH | |
| SCHEMBL11275908 | 0.83 | DRD2 (0.67) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11274506 | 0.82 | SLC6A2 (0.72) | DRD2ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11266439 | 0.81 | DRD2 (0.67) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11219235 | 0.81 | HRH1 (0.80) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11268707 | 0.81 | SLC6A4 (0.65) | DRD2HRH3HRH1KCNH2SMN1; SMN2 | |
| SCHEMBL11262793 | 0.80 | RECQL (0.66) | DRD2HRH3HRH1HTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |