Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.58 |
| ▸ | HRH1 | P35367 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | DRD1 | P21728 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266439 | 0.97 | DRD2 (0.67) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11275993 | 0.87 | LMNA (0.67) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11274506 | 0.85 | SLC6A2 (0.72) | DRD2SLC6A2SLC6A4MAPTDRD4 | |
| SCHEMBL11275967 | 0.84 | DRD2 (0.65) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11219235 | 0.84 | HRH1 (0.80) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11275908 | 0.84 | DRD2 (0.67) | DRD2HRH3HRH1HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL11273968 | 0.83 | HRH1 (0.78) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11276891 | 0.82 | HTR7 (0.66) | DRD2HRH3HRH1HTR2AHTR1A | |
| SCHEMBL11282280 | 0.82 | ADRA1D (0.70) | DRD2HRH3HRH1KCNH2SLC6A2 | |
| SCHEMBL11273685 | 0.82 | HTR2A (0.53) | DRD2HTR2AHTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |