Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11277120 | 0.98 | CA2 (0.37) | CA2POLBMEN1KMT2ALMNA | |
| SCHEMBL11252797 | 0.80 | HTR2C (0.41) | LMNASMN1; SMN2ALDH1A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL11282109 | 0.79 | CARM1 (0.44) | CA2POLBMEN1KMT2ALMNA | |
| SCHEMBL11246015 | 0.78 | SLC6A4 (0.37) | MAPT | |
| Bromide SCHEMBL11273907 | 0.77 | SLC6A4 (0.37) | MAPT | |
| SCHEMBL11256784 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1HEXAHEXB | |
| Bromide SCHEMBL11266456 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HEXAHEXB | |
| SCHEMBL11272848 | 0.76 | MTNR1A (0.47) | POLBALDH1A1MAPK1KDM4E | |
| SCHEMBL4760288 | 0.74 | ALDH1A1 (0.53) | CA2POLBMEN1KMT2ALMNA | |
| SCHEMBL5167815 | 0.73 | ALDH1A1 (0.43) | POLBMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349683-A | ANTICONVULSANTS, ANTIDEPRESSANTS | SYNTHELABO (FR) | 1982-09-14 | — | — | US | disclosed |