Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552536 | 0.85 | KMT2A (0.45) | ALDH1A1NPSR1TDP1CA2KMT2A | |
| Hydrochloric Acid SCHEMBL27494857 | 0.84 | KMT2A (0.44) | ALDH1A1NPSR1TDP1CA2KMT2A | |
| SCHEMBL9830752 | 0.79 | MAOA (0.44) | ALDH1A1CA2KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL11276340 | 0.74 | CA2 (0.38) | ALDH1A1NPSR1TDP1CA2KMT2A | |
| Hydrochloric Acid SCHEMBL11282109 | 0.73 | CARM1 (0.44) | ALDH1A1NPSR1TDP1CA2KMT2A | |
| SCHEMBL11461608 | 0.73 | CA2 (0.37) | ALDH1A1NPSR1TDP1CA2KMT2A | |
| Bromide SCHEMBL11277120 | 0.73 | CA2 (0.37) | ALDH1A1NPSR1TDP1CA2KMT2A | |
| SCHEMBL26606782 | 0.72 | RBP4 (0.43) | ALDH1A1NPSR1TDP1GAAHPGD | |
| SCHEMBL26606788 | 0.72 | ALDH1A1 (0.41) | ALDH1A1NPSR1TDP1GAAHPGD | |
| SCHEMBL27950783 | 0.72 | CA2 (0.39) | ALDH1A1NPSR1TDP1CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014121036-A1 | 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | DEUTERX, LLC (US) | 2014-08-07 | — | — | WO | disclosed |
| EP-1903042-A3 | An improved process for hydrogenation of 5-(substituted Benzylidene) 2,4- Thiazolidine Dione compounds to give corresponding ( +/- ) 5- (substituted Benzyl ) 2,4-Thiazolidine Dione | Cadila Pharmaceuticals Limited (IN) | 2008-05-28 | — | — | EP | disclosed |
| EP-1903042-A2 | An improved process for hydrogenation of 5-(substituted Benzylidene) 2,4- Thiazolidine Dione compounds to give corresponding ( +/- ) 5- (substituted Benzyl ) 2,4-Thiazolidine Dione | Cadila Pharmaceuticals Limited (IN) | 2008-03-26 | — | — | EP | disclosed |
| CN-1150159-C | Intermediate for preparing allyl quinone derivative and prep. of the same | ������������ʽ���� | 2004-05-19 | — | — | CN | disclosed |
| CN-1295060-A | Intermediate for preparing allyl quinone derivative and prep. of the same | EISAI CO LTD (JP) | 2001-05-16 | — | — | CN | disclosed |
| CN-1062549-C | Process for preparing allyl quinone derivative | EISAI KAGAKU KK (JP) | 2001-02-28 | — | — | CN | disclosed |
| CN-1112914-A | Process for producing allyl quinone derivative and intermediate thereof, | EISAI KAGAKU KK (JP) | 1995-12-06 | — | — | CN | disclosed |