Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067260 | 0.78 | ALDH1A1 (0.45) | ALDH1A1RAB9AMAPTTDP1THRB | |
| SCHEMBL10532542 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ANCOA1NCOA3 | |
| SCHEMBL9171990 | 0.75 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1MAPTTDP1 | |
| SCHEMBL30081467 | 0.74 | ALDH1A1 (0.51) | ALDH1A1ERN1TDP1THRBKMT2A | |
| SCHEMBL29950812 | 0.74 | ERN1 (0.42) | ALDH1A1ERN1RAB9ANPC1MAPT | |
| SCHEMBL12152493 | 0.74 | P2RX7 (0.41) | ALDH1A1ERN1RAB9ANPC1MAPT | |
| SCHEMBL371826 | 0.71 | RAB9A (0.53) | ALDH1A1RAB9ANPC1MAPTKMT2A | |
| SCHEMBL4872775 | 0.70 | ERN1 (0.51) | ALDH1A1ERN1MAPTTDP1KMT2A | |
| SCHEMBL2998545 | 0.69 | TERT (0.47) | ALDH1A1ERN1RAB9ANPC1MAPT | |
| SCHEMBL29956214 | 0.69 | TERT (0.47) | ALDH1A1ERN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344956-A | Oxotetrahydrothiophenes | ERCOLI NICOLO | 1982-08-17 | — | — | US | disclosed |