SCHEMBL1127658

SCHEMBL1127658

CC(C)(C)c1ccc(C(=O)c2ccc([S])cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.68
SIRT1 Q96EB6 1/20 0.65
RAB9A P51151 4/20 0.56
NPC1 O15118 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HSP90AA1 P07900 1/20 0.56
PKM P14618 1/20 0.56
HDAC1 Q13547 1/20 0.53
CNR1 P21554 1/20 0.53
CNR2 P34972 1/20 0.53
ALDH1A1 P00352 4/20 0.51
GAA P10253 3/20 0.51
LMNA P02545 1/20 0.51
TDP1 Q9NUW8 1/20 0.50
MEN1 O00255 2/20 0.47
HTT P42858 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPT P10636 2/20 0.47
HIF1A Q16665 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148445 0.89 SRD5A2 (0.83) SRD5A2SIRT1RAB9ANPC1SMN1; SMN2
SCHEMBL10946728 0.89 SRD5A2 (0.83) SRD5A2SIRT1RAB9ANPC1SMN1; SMN2
SCHEMBL12451655 0.87 SRD5A2 (0.73) SRD5A2SIRT1RAB9ANPC1SMN1; SMN2
SCHEMBL12551369 0.87 SRD5A2 (0.73) SRD5A2SIRT1RAB9ANPC1SMN1; SMN2
SCHEMBL20148804 0.87 SRD5A2 (0.73) SRD5A2SIRT1RAB9ANPC1SMN1; SMN2
Hydrochloric Acid SCHEMBL27713186 0.87 SRD5A2 (0.79) SRD5A2SIRT1RAB9ANPC1SMN1; SMN2
SCHEMBL17998030 0.83 SRD5A2 (0.68) SRD5A2SIRT1RAB9ANPC1SMN1; SMN2
SCHEMBL67740 0.82 TSHR (0.55) SRD5A2SIRT1RAB9ANPC1PKM
SCHEMBL23396621 0.81 SRD5A2 (0.70) SRD5A2SIRT1RAB9ANPC1SMN1; SMN2
SCHEMBL10445017 0.81 SRD5A2 (0.70) SRD5A2SIRT1RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024579-B2 Curable liquid composition, particulate filler, and compound TOKYO OHKA KOGYO CO., LTD. (JP) 2024-07-02 US disclosed
US-12011490-B2 Dental photocurable composition excellent in operability and storage stability SHOFU INC. (JP) 2024-06-18 US disclosed
CN-113402657-B Photopolymerization initiator containing aryl iodonium salt for dental photocurable composition 株式会社松风 2024-06-11 CN disclosed
EP-3888616-B1 DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN COLOR TONE SELECTIVITY SHOFU INC (JP) 2024-05-15 EP disclosed
CN-112470551-B Sealing agent for organic electroluminescent display element 电化株式会社 2024-05-14 CN disclosed
CN-113227159-B Composition and method for producing the same 电化株式会社 2024-04-19 CN disclosed
CN-110007557-B Curable composition, film, optical film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2024-04-12 CN disclosed
CN-108957956-B Curable composition, cured product, cured film, display panel, and method for producing cured product 东京应化工业株式会社 2024-04-02 CN disclosed
EP-3881818-B1 DENTAL PHOTOCURABLE COMPOSITIONS COMPRISING PHOTOPOLYMERIZATION INITIATOR COMPRISING AN ARYLIODONIUM SALT SHOFU KK (JP) 2024-03-06 EP disclosed
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
EP-2399905-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION San-Apro Limited (JP) 2011-12-28 EP disclosed
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION SAN-APRO, LTD (JP) 2011-12-08 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed
US-7709598-B2 Fluorinated alkyl fluorophoshoric acid salts of onium and transition metal complex SAN-APRO LIMITED (JP) 2010-05-04 US disclosed
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE SAN-APRO LIMITED (JP) 2009-06-25 US disclosed
EP-1953139-A1 METHOD FOR PRODUCING FLUORINATED SULFONIUM ALKYLFLUOROPHOSPHATE San-Apro Ltd. (JP) 2008-08-06 EP disclosed
US-20070225458-A1 Novel Fluorinated Alkyl Fluorophosphoric Acid Salts of Onium and Ttransition Metal Complex SAN-APRO LIMITED (JP) 2007-09-27 US disclosed
EP-1752463-A1 NOVEL FLUORINATED ALKYLFLUOROPHOSPHORIC ACID SALT OF ONIUM AND TRANSITION METAL COMPLEX San-Apro Limited (JP) 2007-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12011490-B2 Dental photocurable composition excellent in operability and storage stability H1-0, CCND1, CCNT1 SRD5A2 3456/4885SIRT1 258/4885RAB9A 799/4885
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE ARSA, SCO2, DOHH SRD5A2 9/4885SIRT1 1012/4885RAB9A 1097/4885
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST SRD5A2 1856/4885SIRT1 1556/4885RAB9A 3295/4885
US-20070225458-A1 Novel Fluorinated Alkyl Fluorophosphoric Acid Salts of Onium and Ttransition Metal Complex AS3MT, TTR, PFAS SRD5A2 4434/4885SIRT1 4238/4885RAB9A 1953/4885
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION ASIC1, H1-0, IK SRD5A2 2977/4885SIRT1 3277/4885RAB9A 2913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.