SCHEMBL67740

SCHEMBL67740

CC(C)(C)c1ccc([S])cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
LMNA P02545 1/20 0.52
TYR P14679 1/20 0.52
ALDH1A1 P00352 5/20 0.46
HPGD P15428 2/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KIF11 P52732 5/20 0.44
MAPT P10636 2/20 0.41
NPC1 O15118 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41
HDAC1 Q13547 1/20 0.41
SLC22A2 O15244 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL896013 0.97 TSHR (0.52) TSHRLMNATYRALDH1A1HPGD
Fluoride SCHEMBL896015 0.97 TSHR (0.52) TSHRLMNATYRALDH1A1HPGD
Hydrochloric Acid SCHEMBL2026535 0.97 TSHR (0.52) TSHRLMNATYRALDH1A1HPGD
Hydrochloric Acid SCHEMBL943177 0.94 TSHR (0.50) TSHRLMNATYRALDH1A1HPGD
SCHEMBL424728 0.83 TSHR (0.73) TSHRLMNATYRALDH1A1HPGD
SCHEMBL1127658 0.82 SRD5A2 (0.68) LMNAALDH1A1TDP1MAPTNPC1
SCHEMBL1538330 0.80 TSHR (0.61) TSHRLMNATYRALDH1A1HPGD
Hydrogen Peroxide SCHEMBL28677809 0.76 LMNA (0.71) TSHRLMNATYRALDH1A1HPGD
Methylamine SCHEMBL28294591 0.76 TSHR (0.65) TSHRLMNATYRALDH1A1HPGD
SCHEMBL4371460 0.75 TSHR (0.55) TSHRLMNATYRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 864 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114423742-B Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-05-28 CN claimed
EP-2396316-B1 QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2015-07-01 EP claimed
US-8937078-B2 Quinazolinones as prolyl hydroxylase inhibitors JANSSEN PHARMACEUTICA NV (BE) 2015-01-20 US claimed
US-8877748-B2 Heterocyclic fused anthraquinone derivatives, manufacturing method and pharmaceutical composition using thereof NATIONAL DEFENSE MEDICAL CENTER (TW) 2014-11-04 US claimed
US-20100204226-A1 QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2010-08-12 US claimed
EP-0805795-B1 NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES HOECHST SCHERING AGREVO SA (FR) 2000-08-23 EP claimed
EP-0805795-A1 NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 1997-11-12 EP claimed
WO-1996022965-A1 NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1996-08-01 WO claimed
US-4073930-A Carbamoyloximes and oximes and insecticidal and miticidal compositions and methods employing them UNION CARBIDE CORPORATION (US) 1978-02-14 US claimed
CN-110515270-B Photosensitive resin composition, pattern forming method, and method for manufacturing optical semiconductor device 信越化学工业株式会社 2024-07-12 CN disclosed
CN-114981277-B Compound and optical film comprising same 株式会社LG化学 2024-06-11 CN disclosed
CN-113166641-B Organic light-emitting element using polycyclic aromatic derivative compound SFC株式会社 2024-06-04 CN disclosed
US-11993616-B2 Compound and optical film comprising same LG CHEM, LTD. (KR) 2024-05-28 US disclosed
CN-114423742-B Benzotriazole-based compound, light absorber and resin composition 三井化学株式会社 2024-05-28 CN disclosed
US-4101464-A Process for preparing foamed solids using two or more azo compounds PENNWALT CORPORATION (US) 1978-07-18 US disclosed
US-4029615-A AZO COMPOUNDS PENNWALT CORPORATION (US) 1977-06-14 US disclosed
US-3998963-A INSECTICIDE, MITICIDE UNION CARBIDE CORPORATION (US) 1976-12-21 US disclosed
US-3997549-A INSECTICIDE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1976-12-14 US disclosed
US-3993609-A ACID SENSITIVE AZO PROMOTERS PENNWALT CORPORATION (US) 1976-11-23 US disclosed
US-3992377-A 3-Thio-substituted cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204226-A1 QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS P4HA1, EGLN3, EGLN2 TSHR 3968/4885LMNA 2710/4885TYR 333/4885
US-11993616-B2 Compound and optical film comprising same CDH1, OR10J3, CRY1 TSHR 4621/4885LMNA 3926/4885TYR 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.