Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278901 | 0.91 | HTT (0.46) | PTGESNPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL11276626 | 0.88 | NPC1 (0.49) | PTGESNPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL11273766 | 0.88 | SMN1; SMN2 (0.47) | PTGESNPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL11277269 | 0.86 | NPC1 (0.56) | NPC1ALDH1A1MAPTHTTCYP1A2 | |
| SCHEMBL11276599 | 0.83 | TLR7 (0.43) | PTGESNPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL11273156 | 0.82 | MAPK14 (0.49) | MAPTSMN1; SMN2KMT2APKMNPBWR1 | |
| SCHEMBL11267025 | 0.79 | HTT (0.48) | NPC1ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL11272719 | 0.78 | ITGB1 (0.45) | NPC1MAPTHPGDHTTSMN1; SMN2 | |
| SCHEMBL11274203 | 0.78 | TLR7 (0.52) | PTGESNPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL11276064 | 0.77 | HTT (0.46) | NPC1ALDH1A1MAPTKDM4EPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |