Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.66 |
| ▸ | DRD2 | P14416 | 5/20 | 0.65 |
| ▸ | DRD3 | P35462 | 4/20 | 0.65 |
| ▸ | HTR1A | P08908 | 4/20 | 0.65 |
| ▸ | HTR2A | P28223 | 4/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | DRD5 | P21918 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.63 |
| ▸ | HRH1 | P35367 | 5/20 | 0.63 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285664 | 0.96 | HTR7 (0.65) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL11265804 | 0.88 | ADRA1A (0.68) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL11269168 | 0.88 | ADRA1D (0.68) | DRD2DRD3HTR1AHTR2ADRD1 | |
| SCHEMBL11219235 | 0.88 | HRH1 (0.80) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL11282280 | 0.87 | ADRA1D (0.70) | HTR7DRD2DRD3HRH3HRH1 | |
| SCHEMBL11274382 | 0.87 | DRD2 (0.62) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| SCHEMBL11271331 | 0.87 | HRH3 (0.61) | DRD2DRD3HTR1AHTR2ATMEM97 | |
| Hydrochloric Acid SCHEMBL11273968 | 0.87 | HRH1 (0.78) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL11282931 | 0.86 | HRH3 (0.67) | HRH3HRH1HRH2 | |
| SCHEMBL11268707 | 0.85 | SLC6A4 (0.65) | HTR7DRD2DRD3DRD1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |
| EP-0021368-A1 | Piperazinylalkoxyindanes and acid addition salts thereof | MITSUBISHI KASEI CORPORATION (JP) | 1981-01-07 | — | — | EP | disclosed |