Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292614 | 0.89 | OPRM1 (0.39) | TRPV1LMNATSHRMAPTKMT2A | |
| SCHEMBL11286317 | 0.83 | MEN1 (0.39) | LMNATSHRMAPTKMT2AMEN1 | |
| SCHEMBL11277989 | 0.77 | LMNA (0.60) | LMNATSHRMAPTKMT2AOPRM1 | |
| SCHEMBL11235292 | 0.74 | DRD2 (0.44) | LMNATSHRKMT2AMEN1OPRM1 | |
| SCHEMBL11288183 | 0.74 | HTR2A (0.48) | HTR1ADRD2DRD4HTR2ADRD3 | |
| SCHEMBL11225549 | 0.73 | — | — | |
| SCHEMBL11285195 | 0.73 | LMNA (0.41) | TRPV1LMNATSHRMAPTKMT2A | |
| SCHEMBL11224223 | 0.72 | DRD2 (0.38) | LMNATSHRMAPTKMT2AMEN1 | |
| SCHEMBL11284564 | 0.70 | SIGMAR1 (0.64) | TSHROPRM1KCNH2SIGMAR1 | |
| SCHEMBL17543847 | 0.70 | KMT2A (0.44) | LMNATSHRMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353900-A | HYPOTENSIVE, ANTIARRHYTHMIA, CARDIOTONIC, VASODILATORS | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |