Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292614 | 0.87 | OPRM1 (0.39) | MEN1LMNAMAPTKMT2AOPRM1 | |
| SCHEMBL11277990 | 0.83 | TRPV1 (0.35) | MEN1LMNAMAPTKMT2AOPRM1 | |
| SCHEMBL11288906 | 0.78 | LMNA (0.39) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL11285195 | 0.78 | LMNA (0.41) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL11285411 | 0.74 | LMNA (0.36) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL17543847 | 0.74 | KMT2A (0.44) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL11286151 | 0.71 | LMNA (0.38) | MEN1LMNAMAPTKMT2AOPRM1 | |
| SCHEMBL11280929 | 0.71 | HTR2A (0.53) | OPRM1SIGMAR1HTR1ADRD2DRD4 | |
| SCHEMBL11236298 | 0.71 | DRD2 (0.47) | MEN1LMNAKMT2AOPRM1SIGMAR1 | |
| SCHEMBL11284564 | 0.70 | SIGMAR1 (0.64) | OPRM1SIGMAR1KCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353900-A | HYPOTENSIVE, ANTIARRHYTHMIA, CARDIOTONIC, VASODILATORS | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |