SCHEMBL1127835

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15161955	0.84	SMN1; SMN2 (0.44)	THRBCNR1CNR2MAPTKDM4E
	SCHEMBL1127046	0.81	CNR1 (0.46)	L3MBTL1CNR1CNR2KDM4EHPGD
	SCHEMBL1126490	0.77	CNR1 (0.42)	L3MBTL1CNR1CNR2KDM4EHPGD
	SCHEMBL1647570	0.70	L3MBTL1 (0.77)	L3MBTL1THRBMAPTHTTKDM4E
	SCHEMBL15162449	0.70	ALDH1A1 (0.42)	L3MBTL1CNR1CNR2KDM4EHPGD
	SCHEMBL1127685	0.68	POLB (0.39)	CNR1CNR2MAPTKDM4EHPGD
	SCHEMBL1126995	0.68	GFER (0.39)	L3MBTL1THRBCNR1CNR2KDM4E
	SCHEMBL15162305	0.66	KDM4E (0.46)	CNR2MAPTHTTKDM4EHPGD
	SCHEMBL1127404	0.65	HSD17B10 (0.41)	L3MBTL1MAPTHTTKDM4EHPGD
	SCHEMBL13531416	0.64	HPGD (0.73)	THRBMAPTHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.