SCHEMBL358740

SCHEMBL358740

CCCn1sc2ccccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.77
MGLL Q99685 1/20 0.77
CASP3 P42574 5/20 0.74
KAT2A Q92830 1/20 0.60
KAT2B Q92831 1/20 0.60
G6PD P11413 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370720 0.90 FAAH (0.88) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL16601156 0.90 FAAH (0.88) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL203818 0.90 FAAH (0.88) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL11278746 0.89 CASP3 (0.74) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL3147758 0.88 FAAH (0.97) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL24327898 0.87 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL1538488 0.87 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL8621525 0.87 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL11185114 0.87 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B
SCHEMBL1538479 0.87 FAAH (1.00) FAAHMGLLCASP3KAT2AKAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018002-B2 Certain chemical entities, compositions, and methods NEUPHARMA, INC (US) 2024-06-25 US disclosed
US-20230043970-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS NEUPHARMA, INC 2023-02-09 US disclosed
WO-2022202958-A1 NON-AQUEOUS SECONDARY BATTERY POLYMER COMPOSITION AND NON-AQUEOUS SECONDARY BATTERY 旭化成株式会社 2022-09-29 WO disclosed
WO-2022131253-A1 NON-AQUEOUS SECONDARY BATTERY POLYMER COMPOSITION AND NON-AQUEOUS SECONDARY BATTERY 旭化成株式会社 2022-06-23 WO disclosed
CN-113036133-A Polymer composition for nonaqueous secondary battery, and nonaqueous secondary battery 旭化成株式会社 2021-06-25 CN disclosed
CN-113036132-A Polymer composition for nonaqueous secondary battery and nonaqueous secondary battery 旭化成株式会社 2021-06-25 CN disclosed
US-20210053044-A1 Redox Dehydration Coupling Catalysts and Methods Related Thereto UNIV EMORY (US) 2021-02-25 US disclosed
US-10857140-B2 K-Ras modulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-12-08 US disclosed
US-9796700-B2 ERK inhibitors and uses thereof CELGENE CAR LLC (BM) 2017-10-24 US disclosed
US-20170137406-A1 ERK INHIBITORS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY 2017-05-18 US disclosed
EP-0871065-A1 Method for processing a silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-10-14 EP disclosed
EP-0789275-A1 Method for processing silver halide color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1997-08-13 EP disclosed
EP-0747765-A1 Method of processing silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1996-12-11 EP disclosed
EP-0475123-B1 Use of 2-n-alkyl-1,2-benzisothiazolin-3-ones as technical microbiocides RIEDEL DE HAEN AG (DE) 1995-01-04 EP disclosed
EP-0331319-B1 Method for the formation of images KONISHIROKU PHOTO IND (JP) 1994-01-26 EP disclosed
EP-0475123-A1 Use of 2-n-alkyl-1,2-benzisothiazolin-3-ones as technical microbiocides RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1992-03-18 EP disclosed
US-5059516-A Spectrally sensitized to near infared region with cyanine dye, (benz)isothiazole and bromo-nitro substituted alkanol KONICA CORPORATION (JP) 1991-10-22 US disclosed
US-4999282-A Layer of Spectrally Sensitized Light-Sensitive Silver Halide Emulsion KONICA CORPORATION (JP) 1991-03-12 US disclosed
EP-0342987-A1 Silver halide photographic material KONICA CORPORATION (JP) 1989-11-23 EP disclosed
EP-0331319-A1 Method for the formation of images KONICA CORPORATION (JP) 1989-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230043970-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS BRAF, PIK3CA, PLK1 FAAH 2501/4885MGLL 1913/4885CASP3 1080/4885
US-12018002-B2 Certain chemical entities, compositions, and methods BRAF, PIK3CA, PLK1 FAAH 2501/4885MGLL 1913/4885CASP3 1080/4885
US-20170137406-A1 ERK INHIBITORS AND USES THEREOF MAP3K20, MAP3K1, MAPK3 FAAH 3769/4885MGLL 3765/4885CASP3 1691/4885
US-10857140-B2 K-Ras modulators KRAS, HRAS, NRAS FAAH 3260/4885MGLL 3818/4885CASP3 3079/4885
US-20210053044-A1 Redox Dehydration Coupling Catalysts and Methods Related Thereto SCLY, TST, SQOR FAAH 1387/4885MGLL 1210/4885CASP3 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.