Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280415 | 0.83 | RIPK1 (0.39) | GAALMNAMEN1KMT2AHTT | |
| SCHEMBL11221785 | 0.78 | SMN1; SMN2 (0.46) | HPGDGAAALDH1A1MAPK1HTT | |
| SCHEMBL11275087 | 0.77 | HPGD (0.46) | HPGDGAAALDH1A1LMNAMEN1 | |
| SCHEMBL55223 | 0.77 | HPGD (0.46) | HPGDGAAALDH1A1LMNAMEN1 | |
| SCHEMBL11282002 | 0.76 | ACHE (0.53) | HPGDGAAALDH1A1HSD17B10LMNA | |
| SCHEMBL11276287 | 0.75 | HPGD (0.51) | HPGDGAAALDH1A1HSD17B10LMNA | |
| SCHEMBL14645801 | 0.72 | HPGD (0.84) | HPGDGAAALDH1A1HSD17B10LMNA | |
| SCHEMBL1102309 | 0.72 | HPGD (0.84) | HPGDGAAALDH1A1HSD17B10LMNA | |
| SCHEMBL6688685 | 0.72 | HPGD (0.84) | HPGDGAAALDH1A1HSD17B10LMNA | |
| SCHEMBL9414124 | 0.71 | SMN1; SMN2 (0.49) | GAAALDH1A1HSD17B10LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343737-A | Process for production of thiolcarbamates and the thiolcarbamates obtained by said process | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1982-08-10 | — | — | US | disclosed |
| US-4298740-A | REACTION OF TERTIARY HALOGEN COMPOUND WITH THIOLCARBAMIC ACID SALT | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |