SCHEMBL1127993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1128427	0.76	RORA (0.60)	RORARORCRORBPPARAHSD17B10
	SCHEMBL13616802	0.74	RORA (0.59)	RORARORCRORBMAPTPPARA
	SCHEMBL1128000	0.73	RORA (0.60)	RORARORCRORBHSD17B10PSEN1
	SCHEMBL27857846	0.73	RORA (0.43)	RORARORCRORBPPARAPPARG
	SCHEMBL1127961	0.72	RORA (0.62)	RORARORCRORBPSEN1PSEN2
	SCHEMBL25169991	0.72	FAAH (0.59)	MAPTHSD17B10S1PR1KDM4EALDH1A1
	SCHEMBL26239962	0.72	FAAH (0.55)	MAPTHSD17B10S1PR1KDM4EALDH1A1
	SCHEMBL26239688	0.72	ALDH1A1 (0.64)	MAPTHSD17B10KDM4EALDH1A1HPGD
	SCHEMBL23167611	0.72	ALDH1A1 (0.64)	MAPTHSD17B10KDM4EALDH1A1HPGD
	SCHEMBL26239880	0.72	FAAH (0.55)	MAPTHSD17B10S1PR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.