Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | ESR1 | P03372 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GGT1 | P19440 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280439 | 0.91 | KDM4E (0.68) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL9685392 | 0.88 | SLC6A3 (0.63) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL11273464 | 0.88 | KDM4E (0.64) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL6882339 | 0.88 | SLC6A3 (0.55) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL30505635 | 0.88 | SLC6A3 (0.71) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL1979275 | 0.88 | SLC6A3 (0.71) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL8198077 | 0.87 | SLC6A3 (0.62) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL7592511 | 0.87 | SLC6A3 (0.57) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL8777320 | 0.86 | SLC6A3 (0.69) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL9311678 | 0.86 | ESR1 (0.65) | SLC6A3ESR1ALDH1A1TDP1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673724-A | FROM P-OXYBENZOYL AND 2-OXY-6-NAPHTHOYL COMPOUND | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1987-06-16 | — | — | US | claimed |
| CN-116925027-A | Compound for photosensitive resin, heat-resistant resin, photosensitive resin composition, patterned film, and display device | 武汉柔显科技股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-114195688-B | Diamine compound, resin, photosensitive resin composition, and cured film | 武汉柔显科技股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116841121-A | Photosensitive resin composition, method for producing pattern cured film, and use thereof | 武汉柔显科技股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116774524-A | Photosensitive resin composition, method for producing pattern cured product, and use thereof | 武汉柔显科技股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-114561008-B | Alkali-soluble resin, positive photosensitive resin composition, cured film, and display device | 武汉柔显科技股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-114380998-B | Alkali-soluble resin, positive photosensitive resin composition, cured film, and display device | 武汉柔显科技股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-9351980-B2 | Di-aspirin derivatives | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2016-05-31 | — | — | US | disclosed |
| US-9351980-B2 | Di-aspirin derivatives | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2016-05-31 | — | — | US | disclosed |
| US-20130035317-A1 | Di-Aspirin Derivatives | THE UNIVERISTY OF WOLVERHAMPTON (GB) | 2013-02-07 | — | — | US | disclosed |
| US-8258293-B2 | Tetrahydroquinoline derivatives | MSD OSS B.V. (NL) | 2012-09-04 | — | — | US | disclosed |
| US-20120202996-A1 | TETRAHYDROQUINOLINE DERIVATIVES | N.V. ORGANON (NL) | 2012-08-09 | — | — | US | disclosed |
| US-8058441-B2 | For control fertility, contraception, breast cancer, prostate cancer and endometriosis; modulating activity of the follicle stimulating hormone (FSH) receptor; 1-Acetyl-6-(tert-butoxycarbonyl)amino-4-phenyl-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline | N.V. ORGANON (NL) | 2011-11-15 | — | — | US | disclosed |
| WO-2011098839-A2 | DI-ASPIRIN DERIVATIVES | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2011-08-18 | — | — | WO | disclosed |
| EP-1406628-B1 | TETRAHYDROQUINOLINE DERIVATIVES | AKZO NOBEL NV (NL) | 2006-03-08 | — | — | EP | disclosed |
| US-20040236109-A1 | Tetrahydroquinoline derivatives | MERCK SHARP & DOHME B.V. (NL) | 2004-11-25 | — | — | US | disclosed |
| EP-1406628-A1 | TETRAHYDROQUINOLINE DERIVATIVES | Akzo Nobel N.V. (NL) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003004028-A1 | TETRAHYDROQUINOLINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2003-01-16 | — | — | WO | disclosed |
| US-4673724-A | FROM P-OXYBENZOYL AND 2-OXY-6-NAPHTHOYL COMPOUND | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1987-06-16 | — | — | US | disclosed |
| US-4259383-A | PEROXY COMPOUNDS | STERLING DRUG INC. (US) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202996-A1 | TETRAHYDROQUINOLINE DERIVATIVES | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ODC1, COX6C | KDM4E 903/4885HSD17B10 1860/4885LMNA 2193/4885 |
| US-20040236109-A1 | Tetrahydroquinoline derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AOC2, HTR3C | KDM4E 845/4885HSD17B10 1212/4885LMNA 1631/4885 |
| US-20130035317-A1 | Di-Aspirin Derivatives | SDHA, DLD, DPYD | KDM4E 2764/4885HSD17B10 987/4885LMNA 4485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.