Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | AHCY | P23526 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569301 | 0.80 | KMT2A (0.49) | ALDH1A1 | |
| SCHEMBL10569307 | 0.80 | KMT2A (0.49) | ALDH1A1 | |
| SCHEMBL10570833 | 0.80 | KMT2A (0.49) | ALDH1A1 | |
| SCHEMBL11280894 | 0.78 | AHCY (0.64) | ADORA2AAHCYADORA1ALDH1A1 | |
| SCHEMBL11283124 | 0.78 | L3MBTL1 (0.41) | ADORA2AAHCYADORA1ALDH1A1 | |
| SCHEMBL11289245 | 0.78 | L3MBTL1 (0.41) | ADORA2AAHCYADORA1ALDH1A1 | |
| SCHEMBL13997084 | 0.78 | ADORA2A (0.43) | ADORA2AAHCYADORA1ALDH1A1 | |
| SCHEMBL28115671 | 0.74 | ADORA2A (0.56) | ADORA2AAHCYADORA1ALDH1A1 | |
| SCHEMBL28025689 | 0.71 | ALDH1A1 (0.46) | ADORA2AAHCYADORA1ALDH1A1 | |
| SCHEMBL11280453 | 0.68 | ADORA2A (0.31) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052964-A1 | Adenine derivatives possessing pharmacological activity | BEECHAM GROUP PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0052964-A1 | Adenine derivatives possessing pharmacological activity | BEECHAM GROUP PLC (GB) | 1982-06-02 | — | — | EP | disclosed |