Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22623610 | 0.73 | CRBN (0.39) | CRBNDDB1 | |
| SCHEMBL18065790 | 0.71 | MAP3K14 (0.40) | MAP3K14CRBNDDB1MAPT | |
| SCHEMBL625564 | 0.71 | MAP3K14 (0.40) | MAP3K14CRBNDDB1MAPT | |
| SCHEMBL11835120 | 0.70 | MAP3K14 (0.43) | MAP3K14CRBNDDB1 | |
| SCHEMBL36369 | 0.70 | MAP3K14 (0.43) | MAP3K14CRBNDDB1 | |
| SCHEMBL11047080 | 0.70 | MAP3K14 (0.43) | MAP3K14CRBNDDB1 | |
| SCHEMBL5086277 | 0.68 | MAP3K14 (0.41) | MAP3K14CRBNDDB1 | |
| SCHEMBL4226223 | 0.68 | MAP3K14 (0.41) | MAP3K14CRBNDDB1 | |
| SCHEMBL4226226 | 0.68 | MAP3K14 (0.41) | MAP3K14CRBNDDB1 | |
| SCHEMBL24629023 | 0.67 | CA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364958-A | 1-Substituted-3-cycloalkyl-sulfonyl-pyrrolidine-2,5-dione derivatives and fungicidal compositions thereof | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-12-21 | — | — | US | claimed |
| US-4364958-A | 1-Substituted-3-cycloalkyl-sulfonyl-pyrrolidine-2,5-dione derivatives and fungicidal compositions thereof | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-12-21 | — | — | US | disclosed |