Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282236 | 0.90 | CNR2 (0.48) | CNR2ALDH1A1PYGLLMNAITGA4 | |
| SCHEMBL11278294 | 0.82 | CNR2 (0.49) | CNR2ALDH1A1NPSR1ITGA4ITGB7 | |
| SCHEMBL11276064 | 0.78 | HTT (0.46) | ALDH1A1CYP1A2PYGLLMNANPSR1 | |
| SCHEMBL11274211 | 0.78 | PYGL (0.43) | ALDH1A1CYP1A2CYP2C19PYGLLMNA | |
| SCHEMBL11273034 | 0.73 | SMN1; SMN2 (0.41) | ALDH1A1CYP1A2PYGLNPSR1KMT2A | |
| SCHEMBL11271650 | 0.72 | RXFP1 (0.46) | CYP1A2KMT2A | |
| SCHEMBL11276626 | 0.70 | NPC1 (0.49) | ALDH1A1CYP1A2PYGLLMNANPSR1 | |
| SCHEMBL26014019 | 0.69 | CNR2 (0.69) | CNR2CYP1A2CNR1 | |
| SCHEMBL11285219 | 0.68 | PYGL (0.46) | ALDH1A1CYP1A2CYP2C19PYGLLMNA | |
| SCHEMBL11267025 | 0.68 | HTT (0.48) | ALDH1A1CYP1A2PYGLLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |