Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914370 | 0.76 | ALDH1A1 (0.58) | TSHRDAONAPRTALDH1A1HIF1A | |
| SCHEMBL11362793 | 0.76 | ALDH1A1 (0.39) | TSHRDAONAPRTALDH1A1HIF1A | |
| SCHEMBL10486356 | 0.76 | MAOA (0.47) | TSHRDAONAPRTALDH1A1HIF1A | |
| SCHEMBL5181926 | 0.75 | POLB (0.42) | TSHRDAONAPRTALDH1A1HIF1A | |
| SCHEMBL27994240 | 0.71 | KCNN4 (0.44) | TSHRALDH1A1HIF1AMAPK1CES1 | |
| SCHEMBL27361874 | 0.70 | ALDH1A1 (0.56) | TSHRDAONAPRTALDH1A1HIF1A | |
| SCHEMBL8110239 | 0.69 | L3MBTL1 (0.46) | TSHRDAONAPRTALDH1A1HIF1A | |
| Benzoic Acid SCHEMBL11359136 | 0.69 | TSHR (0.78) | TSHRDAONAPRTALDH1A1HIF1A | |
| SCHEMBL11378361 | 0.69 | CES1 (0.52) | ALDH1A1MAPK1CES1MEN1MAPT | |
| Benzene SCHEMBL10830313 | 0.67 | TSHR (0.37) | TSHRDAONAPRTALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365062-A | BACTERICIDAL ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1982-12-21 | — | — | US | claimed |