SCHEMBL8110239

SCHEMBL8110239

c1ccc([C](CC[C](c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
MAPT P10636 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
GAA P10253 2/20 0.46
LMNA P02545 1/20 0.46
NR4A2 P43354 1/20 0.46
CES1 P23141 4/20 0.46
MAPK1 P28482 2/20 0.46
CYP3A4 P08684 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CES2 O00748 3/20 0.45
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
DAO P14920 1/20 0.45
NAPRT Q6XQN6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27827492 0.85 TDP1 (0.42) L3MBTL1MAPTTDP1GAALMNA
SCHEMBL392449 0.83 CES2 (0.56) L3MBTL1MAPTTDP1LMNACES1
SCHEMBL6003390 0.83 MAPT (0.39) L3MBTL1MAPTTDP1GAALMNA
SCHEMBL6497058 0.81 KEAP1 (0.56) MAPTTDP1MAPK1KDM4EHPGD
SCHEMBL28019637 0.81 CES2 (0.54) L3MBTL1MAPTTDP1LMNACES1
SCHEMBL16496871 0.79 MAOA (0.43) L3MBTL1MAPTTDP1LMNAKMT2A
SCHEMBL3191159 0.79 PTGS2 (0.61) CES1CES2ALDH1A1
SCHEMBL6003383 0.79 TDP1 (0.41) L3MBTL1MAPTTDP1LMNANR4A2
SCHEMBL3087344 0.78 CES1 (0.43) L3MBTL1MAPTTDP1GAACES1
SCHEMBL7785327 0.77 ALDH1A1 (0.41) L3MBTL1MAPTLMNACES1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143847-A SUCH AS METHACRYLATE POLYMERS OF NARROW MOLECULAR WEIGHT DISTRIBUTION BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed