Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | AOC2 | O75106 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110146 | 0.85 | HPGD (0.48) | HPGDTSHRGABRA1GABRB2DYRK1A | |
| SCHEMBL5695473 | 0.84 | CA2 (0.46) | HPGDTSHRGABRA1GABRB2NISCH | |
| SCHEMBL28450234 | 0.83 | GABRA1 (0.56) | HPGDTSHRGABRA1GABRB2DYRK1A | |
| SCHEMBL28450236 | 0.83 | GABRA1 (0.56) | HPGDTSHRGABRA1GABRB2DYRK1A | |
| SCHEMBL28456004 | 0.80 | HPGD (0.43) | HPGDTSHRGABRA1GABRB2DYRK1A | |
| SCHEMBL7804953 | 0.80 | HPGD (0.43) | HPGDTSHRGABRA1GABRB2DYRK1A | |
| SCHEMBL30151789 | 0.78 | HPGD (0.59) | HPGDTSHRGABRA1GABRB2DYRK1A | |
| SCHEMBL30151836 | 0.77 | HPGD (0.62) | HPGDTSHRGABRA1GABRB2DYRK1A | |
| SCHEMBL860446 | 0.75 | HPGD (0.59) | HPGDTSHRNISCHMAOBAOC2 | |
| SCHEMBL29974170 | 0.75 | HPGD (0.59) | HPGDTSHRNISCHMAOBAOC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332817-A | CARBAMATES WITH ALKANEDIOLS | CELANESE CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
| US-4226881-A | ARYL OR HETEROCYCLIC N-ALKYL CARBAMATE, SYNERGISTIC ALKANEDIOL | CELANESE CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |