Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | USP14 | P54578 | 2/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283234 | 0.84 | ALDH1A1 (0.40) | NOTUMKDM4ESMN1; SMN2TDP1TSHR | |
| SCHEMBL11181865 | 0.76 | DRD2 (0.45) | POLBMAPT | |
| SCHEMBL16713034 | 0.74 | PTGS2 (0.51) | NOTUMGRM5KDM4EPOLBPTGS2 | |
| SCHEMBL6510547 | 0.71 | PTGS2 (0.39) | NOTUMGRM5KDM4EPOLBPTGS2 | |
| SCHEMBL22290195 | 0.68 | KCNH2 (0.40) | NOTUMSMN1; SMN2MAPTLMNA | |
| SCHEMBL23147891 | 0.67 | NOTUM (0.49) | NOTUMGRM5KDM4EPOLBPTGS2 | |
| SCHEMBL23147167 | 0.67 | KDM4E (0.46) | NOTUMGRM5KDM4EPOLBPTGS2 | |
| SCHEMBL29812412 | 0.66 | L3MBTL1 (0.47) | NOTUMGRM5KDM4EPOLBPTGS2 | |
| SCHEMBL12247832 | 0.66 | MEN1 (0.49) | KDM4EPTGS2SMN1; SMN2PIK3CAMTOR | |
| SCHEMBL14248904 | 0.65 | POLB (0.46) | KDM4EPOLBTSHRMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338453-A | Aminoalkyl-1,2,4-triazoles | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | disclosed |