Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198990 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2P4HBTSHRALDH1A1 | |
| SCHEMBL79176 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2P4HBTSHRALDH1A1 | |
| SCHEMBL9198984 | 0.74 | GABRA1 (0.41) | GABRA1GABRB2P4HBTSHRALDH1A1 | |
| SCHEMBL11293114 | 0.71 | NPY2R (0.34) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL7984395 | 0.71 | PTGS2 (0.63) | GABRA1GABRB2P4HBTSHRTDP1 | |
| SCHEMBL24443105 | 0.69 | P4HB (0.41) | GABRA1GABRB2P4HBTSHRALDH1A1 | |
| SCHEMBL6932141 | 0.68 | TRPA1 (0.41) | GABRA1GABRB2P4HBTSHRALDH1A1 | |
| SCHEMBL11855485 | 0.67 | P4HB (0.39) | GABRA1GABRB2P4HBTSHRALDH1A1 | |
| SCHEMBL24743672 | 0.67 | P4HB (0.39) | GABRA1GABRB2P4HBTSHRALDH1A1 | |
| SCHEMBL337809 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010580-B1 | 2-(1-METHYL-PROPYN-2-YL-THIO)-PHENYL-N-METHYLCARBAMATE, PROCESS FOR ITS PREPARATION AND ITS USE IN COMBATING PESTS | BASF Aktiengesellschaft (DE) | 1982-09-29 | — | — | EP | claimed |
| US-4239775-A | 2-(1-Methylpropyn-2-yl-thio)-phenyl-N-methylcarbamate and its use for combating pests of the Acarina order | BASF AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |