Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977245 | 0.86 | ALDH1A1 (0.53) | POLBALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL11283363 | 0.85 | SMN1; SMN2 (0.50) | POLBALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL21859008 | 0.81 | LMNA (0.54) | POLBALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL3318354 | 0.80 | LMNA (0.53) | POLBALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL8703572 | 0.80 | ALDH1A1 (0.62) | POLBALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL5094504 | 0.79 | LMNA (0.58) | POLBALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL11582004 | 0.79 | ALDH1A1 (0.53) | POLBALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL11286741 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTTSHRLMNA | |
| SCHEMBL11348393 | 0.78 | SMN1; SMN2 (0.52) | POLBALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL9775959 | 0.78 | ALDH1A1 (0.52) | POLBALDH1A1SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341784-A | BACTERICIDES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1982-07-27 | — | — | US | disclosed |
| EP-0027752-A1 | Naphthyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1981-04-29 | — | — | EP | disclosed |