Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348393 | 0.85 | SMN1; SMN2 (0.52) | LMNATSHRMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL3814272 | 0.84 | TSHR (0.41) | LMNATSHRMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL3696586 | 0.81 | LMNA (0.64) | LMNATSHRMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL5792568 | 0.79 | LMNA (0.40) | LMNATSHRMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL12107837 | 0.79 | LMNA (0.41) | LMNATSHRMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL11289462 | 0.79 | POLB (0.53) | LMNATSHRMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL3977245 | 0.79 | ALDH1A1 (0.53) | LMNATSHRMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL3704116 | 0.79 | ALDH1A1 (0.53) | LMNATSHRMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL11789908 | 0.79 | SMN1; SMN2 (0.79) | LMNATSHRMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL11283363 | 0.78 | SMN1; SMN2 (0.50) | LMNATSHRMAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402674-B2 | 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments | SANOFI-AVENTIS DEUTSCHLAND GMBH, (DE) | 2008-07-22 | — | — | US | disclosed |
| US-20050182085-A1 | 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182085-A1 | 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments | SLC5A2, CYP2A7, GLS | LMNA 2195/4885TSHR 3679/4885MAPT 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.