Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297976 | 0.91 | MAPT (0.41) | FPR2TSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11299822 | 0.90 | ABCB11 (0.42) | FPR2RAB9AMAPTMME | |
| SCHEMBL11290034 | 0.81 | TSHR (0.37) | FPR2HPGDTSHRSMN1; SMN2MAOB | |
| SCHEMBL11296990 | 0.80 | LMNA (0.39) | MAPTKMT2AMEN1 | |
| SCHEMBL11296871 | 0.78 | ABCB11 (0.56) | MAPTMAOBMMEKMT2A | |
| SCHEMBL11290364 | 0.76 | EPHX1 (0.44) | TSHRRAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL11018732 | 0.76 | RAB9A (0.37) | FPR2TSHRRAB9AMMEKMT2A | |
| SCHEMBL7429540 | 0.75 | MME (0.36) | TSHRRAB9AMMEKMT2AMEN1 | |
| SCHEMBL11295533 | 0.74 | LMNA (0.48) | RAB9ANPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL11265051 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |