Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254977 | 0.80 | LDHA (0.57) | PIK3CDPIK3R1CYP3A4TSHRALDH1A1 | |
| SCHEMBL11109561 | 0.78 | DRD2 (0.47) | PIK3CDPIK3R1DRD2DRD4DRD3 | |
| SCHEMBL11112404 | 0.74 | PIK3CD (0.53) | PIK3CDPIK3R1DRD2DRD4DRD3 | |
| SCHEMBL11111880 | 0.73 | SMN1; SMN2 (0.43) | PIK3CDPIK3R1TSHRALDH1A1GALR3 | |
| SCHEMBL11286500 | 0.73 | KDM4E (0.45) | PIK3CDPIK3R1CYP3A4ALDH1A1HPGD | |
| SCHEMBL11105916 | 0.73 | S1PR4 (0.47) | PIK3CDPIK3R1CYP3A4TSHRALDH1A1 | |
| SCHEMBL11102550 | 0.73 | DRD2 (0.45) | PIK3CDPIK3R1CYP3A4TSHRALDH1A1 | |
| SCHEMBL11290156 | 0.71 | LMNA (0.46) | PIK3CDPIK3R1CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL11107144 | 0.71 | L3MBTL1 (0.45) | PIK3CDPIK3R1CYP3A4ALDH1A1GALR3 | |
| SCHEMBL11103205 | 0.71 | GALR3 (0.40) | PIK3CDPIK3R1GALR3NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |